|
|
 |
|
|
|
| |
 Selected
Papers 
|
|
Noncanonical DNA
|
|
1) AC-motif: a DNA motif containing adenine and cytosine repeat plays a role in gene regulation.
Nucleic Acids Res. 2021 Sep 1:gkab728.
2) The effect of hairpin loop on the structure and gene expression activity of the long-loop G-quadruplex.
Nucleic Acids Res. 2021 Aug 27:gkab739.
3) Genome-wide analysis of regulatory G-quadruplexes affecting gene expression in human cytomegalovirus
PLoS Pathog. 2018 Sep 28;14(9):e1007334.
4) Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res. 2018 Nov 2;46(19):10504-10513.
5) Examining cooperative binding of Sox2 on DC5 regulatory element upon complex formation with Pax6 through excess electron transfer assay.
Nucleic Acids Res. 2016 Aug 19;44(14):e125.
6) Solution structure of the Z-DNA binding domain of PKR-like protein kinase (PKZ) from Carassius auratus and quantitative analyses of the intermediate complex during B-Z transition.
Nucleic Acids Res. 2016 Apr 7;44(6):2936-48.
7) Single molecule visualization and characterization of Sox2-Pax6 complex formation on a regulatory DNA element using a DNA origami frame.
Nano Lett. 2014 May 14;14(5):2286-92.
8) Distinct Z-DNA binding mode of a PKR-like protein kinase containing a Z-DNA binding domain.
Nucleic Acids Res. 2014 May 1;42(9):5937-48.
9 ) Solution structure of the Z-alph domain of human DAI and its binding modes to B- and Z-DNAs
Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6921-6.
10) Intrinsic Z-DNA Is Stabilized by the Conformational Selection Mechanism of Z-DNA-Binding Proteins.
J Am Chem Soc. 2011 Feb 2;133(4):668-71.
11) Base extrusion is found at helical junctions between right- and left-handed forms of DNA and RNA.
Nucleic Acids Res. 2009 Jul;37(13):4353-59. Epub 2008 May 21
12) Crystal Structure of a B-DNA-Z-DNA junction Reveals Two Extruded Bases.
Nature. 2005 Oct 20;437(7062):1183-6.
Deubiquitinase & Protein homeostasis
1) Ubiquitin-Specific Protease 21 Promotes Colorectal Cancer Metastasis by Acting as a Fra-1 Deubiquitinase.
Cancers 2020, Jan 14; 12(1), 207.
2) A Selective Inhibitor of Ubiquitin-Specific Protease 4 Suppresses Colorectal Cancer Progression by Regulating b-catenin Signaling.
Cell Physiol Biochem 2019;53(1):157-171.
3) Ubiquitin-specific protease 4 (USP4) suppresses myoblast differentiation in a catalytic-independent manner.
Cellular signaling. 2017 Mar 21;35:48-60.
4) Ubiquitin-specific protease 4 controls metastatic potential through -catenin stabilization in brain metastatic lung adenocarcinoma.
Sci Rep. 2016 Feb 17;6:21596. doi: 10.1038/srep21596.
5) Ubiquitin specific protease 4 positively regulates the WNT/beta-catenin signaling in colorectal cancer.
Mol Oncol. 2015 Nov;9(9):1834-51.
6) Crystal Structure of a Small Heat-Shock Protein.
Nature. 1998 Aug 6;394(6693):595-9.
7) Small Heat Shock Protein of Methanococcus janaschii, a Hyperthermophile.
Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9129-33.
Cell Reprogramming
1) Exosome-Mediated Differentiation of Mouse Embryonic Fibroblasts and Exocrine Cells into ет-Like Cells and the Identification of Key miRNAs for Differentiation.
Biomedicines. 2020 Nov 9;8(11):E485.
2) Chemical induced conversion of mouse fibroblasts and human adipose-derived stem cells into skeletal muscle-like cells.
Biomaterials. 2019 Feb;193:30-46.
3) Small molecule-induced cellular conversion.
Chem Soc Rev. 2017 Oct 16;46(20):6241-6254.
4) A synthetic DNA-binding inhibitor of SOX2 guides human induced pluripotent stem cells to differentiate into cardiac mesoderm.
Nucleic Acids Res. 2017 Sep 19;45(16):9219-9228.
5) Combining suppression of stemness with lineage-specific induction leads to selective conversion of pluripotent cells into functional neurons.
Chemistry and Biology 2015 Nov 19;22(11):1512-20.
6) Inhibition of master transcription factors in pluripotent cells induces early stage differentiation.
Proc Natl Acad Sci U S A. 2014 Feb 14; 111(5): 1778-83.
Antimicrobial Resistance & Bacterial Signaling
1) An Antibacterial Nanorobotic Approach for the Specific Targeting and Removal of Multiple Drug-Resistant Staphylococcus aureus.
Small. 2021 Apr 10:e2100257.
2) Targeting Mannitol Metabolism as an Alternative Antimicrobial Strategy Based on the Structure-Function Study of Mannitol-1-Phosphate Dehydrogenase in Staphylococcus aureus.
MBio. 2019 Jul 9;10(4). pii: e02660-18.
3) Total synthesis of Xanthoangelol B and its various fragments: towards inhibition of virulence factor production of Staphylococcus aureus.
J Med Chem. 2018 Nov 2; 23, 10473?10487
4) Coupling of radiofrequency with magnetic nanoparticles treatment as an alternative physical antibacterial strategy against multiple drug resistant bacteria.
Sci Rep. 2016 Sep 27;6:33662.
5) Structural studies on the extracellular domain of sensor histidine kinase YycG from Staphylococcus aureus and its functional implications.
J Mol Biol. 2016 Jul 4. pii: S0022-2836(16)30241-8.
6) Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor.
Acta Crystallogr D Biol Crystallogr. 2014 Mar;70(Pt 3):694-707
7) Four Helical-Bundle Structure of the Cytoplasmic Domain of a Serine Chemotaxis Receptor.
Nature. 1999 Aug 19;400(6746):787-92.
Nanobiomaterials
1) Bioinorganic Nanohybrid Catalyst for Multistep Synthesis of Acetaminophen, an Analgesic.
ACS Appl. Mater. Interfaces.2016,8(44), pp 30058-30065.
2) Photocurrent enhancement of SiNW-FETs by integrating protein-shelled CdSe quantum dots
Nanoscale, 2016 Jan 28;8:1921-1925.
3) Distinct Rayleigh Scattering from Hot Spot Mutant p53 Proteins Reveals Cancer Cells.
Small. 2014 Jul;10(14):2954-62.
4) Radiofrequency treatment enhances the catalytic function of an immobilized nanobiohybrid catalyst
Nanoscale. 2014 Jun 7;6(11):6009-17.
5) Combining Protein-Shelled Platinum Nanoparticles with Graphene to Build a Bionanohybrid Capacitor.
ACS Nano. 2014 Dec 23;8(12):12120-9.
6) The effect of protein shells on the antioxidant activity of protein-encapsulated platinum nanoparticles
J. Mater. Chem., 2012 Feb 2:,22(5): 1774-1780.
7) Platinum nanoparticles encapsulated by aminopeptidase: a multifunctional bioinorganic nanohybrid catalyst
Angew Chem Int Ed Engl. 2011 Dec 9;50(50):11924-9.
|
|
structures
|
|
|
Structures deposited at Protein Data bank (PDB)
|
|
|
|
| |
| |
|
|
 |
